Prostaglandin E1
SIGMA/P8908 - synthetic, powder, BioReagent, suitable for cell culture
Synonym: (11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-enoic acid; Alprostadil; PGE1
CAS Number: 745-65-3
Empirical Formula (Hill Notation): C20H34O5
Molecular Weight: 354.48
EC Number: 212-017-2
MDL Number: MFCD00077860
Linear Formula: C20H34O5
Product Type: Chemical
| assay | ≥98% (HPLC) |
| biological source | synthetic |
| form | powder |
| InChI | 1S/C20H34O5/c1-2-3-6-9-15 |
| InChI key | GMVPRGQOIOIIMI-DWKJAMRDSA |
| potency | 0.25-100 ng/mL |
| product line | BioReagent |
| Quality Level | 200  |
| SMILES string | O=C1[C@H](CCCCCCC(O)=O)[C |
| solubility | acetone: 10 mg/mL, clear, colorless |
| storage temp. | −20°C |
| technique(s) | cell culture | mammalian: suitable |
| Application: | Prostaglandin E1 may be used in cell culture to protect human umbilical vein endothelial cells (HUVEC) from injury induced by hydrogen peroxide. |
| Biochem/physiol Actions: | Prostaglandin E1 (PGE1) aids in the relaxation of corporal cavernosal tissue. It helps to preserve the patency of the ductus arteriosus. It is used to treat erectile dysfunction (ED). |
| General description: | Prostaglandin E1 (PGE1) is a vasodilator. |
| Physical form: | powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P301 + P310 + P330 |
| Hazard Codes | Xn |
| Risk Statements | 61-22 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352209 |