Pyridoxal 5′-phosphate hydrate

SIGMA/P9255 - ≥98%

Synonym: Pyridoxal phosphate; 3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde; Codecarboxylase; PLP; Pyridoxal 5-phosphate

CAS Number: 853645-22-4
Empirical Formula (Hill Notation): C₈H₁₀NO₆P · xH₂O
Molecular Weight: 247.14 (anhydrous basis)
EC Number: 200-208-3
MDL Number: MFCD00006333
Linear Formula: C₈H₁₀NO₆P · xH₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-P9255-1G	1 g	$65.40 1/EA	Add To Favorites
45-P9255-5G	5 g	$235.00 1/EA	Add To Favorites
45-P9255-25G	25 g	$810.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: P9255-25G

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98%
biological source	synthetic (organic)
color	beige
	off-white to yellow
form	powder
InChI	1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
InChI key	NGVDGCNFYWLIFO-UHFFFAOYSA-N
mp	140-143 °C
Quality Level	200
SMILES string	CC1=NC=C(COP(O)(O)=O)C(C([H])=O)=C1O
storage temp.	−20°C
technique(s)	HPLC: suitable

Application:	Pyridoxal 5′-phosphate hydrate has also been used: • as a reference standard to quantify vitamin B₆ in feed and digesta samples using high performance liquid chromatography (HPLC) • in D-amino acid transaminase reaction(10) • as a cofactor for L-glutamic acid decarboxylase
Biochem/physiol Actions:	Pyridoxal 5′-phosphate (PLP) aids in carbohydrate and fat metabolism by serving as a cofactor. It is majorly responsible for catalyzing the enzymatic reactions involved in sphingolipid synthesis and neurotransmitter (dopamine and serotonin) synthesis. PLP is used in the studies of PLP-dependent enzyme active sites. PLP is also a cofactor for a wide range of enzymes including mitochondrial 5-Aminolevulinic acid synthase (ALAS) cysteine desulfurase, cystathionine γ-synthase (CGS), ornithine 4,5-aminomutase (OAM), and D-serine dehydratase.
General description:	Pyridoxal 5′-phosphate (PLP) is synthesized in a multiple-step process. The two pathways inlcude pyridoxal phosphate biosynthetic protein (PdxA)- pyridoxine-5′-phosphate synthase (PdxJ) pathway and the pyridoxal 5′-phosphate synthase subunit PDX1/PDX2 pathway. It is the active form of pyridoxine.
Packaging:	1, 5, 25 g in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98%
mp	140-143 °C
Storage Temp.	−20°C
UNSPSC	12352205

To Order From a Quote