Psychosine from bovine brain

SIGMA/P9256 - lyophilized powder, ≥98% (TLC)

Synonym: 1-β-D-Galactosylsphingosine

CAS Number: 2238-90-6
Empirical Formula (Hill Notation): C₂₄H₄₇NO₇
Molecular Weight: 461.63
MDL Number: MFCD00057505
Linear Formula: C₂₄H₄₇NO₇
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-P9256-1MG	1 mg	$122.00 1/EA		Add To Favorites
45-P9256-10MG	10 mg	$558.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (TLC)
form	lyophilized powder
InChI	1S/C24H47NO7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(27)18(25)17-31-24-23(30)22(29)21(28)20(16-26)32-24/h14-15,18-24,26-30H,2-13,16-17,25H2,1H3/b15-14+/t18-,19+,20+,21-,22-,23+,24+/m0/s1
InChI key	HHJTWTPUPVQKNA-PIIMIWFASA-N
Quality Level	200
SMILES string	CCCCCCCCCCCCCC=C[C@@H](O)[C@@H](N)CO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
storage temp.	−20°C

Application:	Psychosine has been used as a lipid in lipid-protein overlay binding assay.
Biochem/physiol Actions:	Psychosine is a neurotoxic lysosphingolipid and a glycolipid precursor for the synthesis of cerebrosides. It is synthesized from galactosylceramide, phrenosin. Elevated psychosine levels are implicated in Krabbe disease. It mediates demyelination and consequently oligodendrocytes degeneration. Psychosine is also correlated to neurological disease, Globoid cell leukodystrophy (GLD), where in galactosylceramidase (GALC) enzyme deficiency leads to its accumulation.
Packaging:	1 mg in glass bottle
Packaging:	10 mg in poly bottle

Hazard Codes	Xn
Risk Statements	20/21/22
Safety Statements	36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (TLC)
Storage Temp.	−20°C
UNSPSC	12352211

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