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Poly(deoxyguanylic-deoxycytidylic) acid sodium salt

SIGMA/P9389 - double stranded, alternating copolymer

Synonym: Poly(dG-dC) • Poly(dG-dC)

CAS Number: 90385-88-9
MDL Number: MFCD00131968
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-P9389-10UN 10 units
 $751.00
1/EA		 Add To Favorites
45-P9389-25UN 25 units
 $1600.00
1/EA		 Add To Favorites
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biological source synthetic (organic)
form powder or solid
Quality Level 200 
storage temp. −20°C
Application: Poly(deoxyguanylic-deoxycytidylic) acid (Poly(dG-dC) • Poly(dG-dC)) is an alternating copolymer, self-complementary, double-stranded DNA model for conformational studies of DNA structure dynamics and drug interaction.
Application: Poly(deoxyguanylic-deoxycytidylic) acid sodium salt has been used:
• in electrophoretic mobility shift assay of transcription factor IIIB complex
• as synthetic copolymers for circular dichroism (CD) spectroscopy studies
• as a positive control in liquid scintillation counting
General description: Poly(deoxyguanylic-deoxycytidylic) acid (poly(dG-dC)) undergoes salt dependent conformational transition. Under high-salt, it exists as a left-handed double helix and at low-salt it displays B-DNA conformation. However on immobilization, poly(dG-dC) takes up A DNA form.
Other Notes: Alternating copolymer; self-complementary, form double-stranded complex
Other Notes: One unit will yield an A260 of 1.0 in 1.0 ml 20 mM sodium phosphate/100 mM NaCl, pH 7.0 (1cm light path).
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. −20°C
UNSPSC 41106305

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