Sodium palmitate
SIGMA/P9767 - ≥98.5%
Synonym: Hexadecanoic acid sodium salt; Palmitic acid sodium salt
CAS Number: 408-35-5
Empirical Formula (Hill Notation): C16H31NaO2
Molecular Weight: 278.41
EC Number: 206-988-1
MDL Number: MFCD00002749
Linear Formula: CH3(CH2)14COONa
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: P9767-50G
This image depicts SKU: P9767-50G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: P9767-10G
This image depicts SKU: P9767-10G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: P9767-5G
This image depicts SKU: P9767-5G
| assay | ≥98.5% |
| biological source | plant (palm) |
| form | powder |
| functional group | ester |
| InChI | 1S/C16H32O2.Na/c1-2-3-4-5 |
| InChI key | GGXKEBACDBNFAF-UHFFFAOYSA |
| lipid type | saturated FAs |
| mp | 283-290 °C (lit.) |
| Quality Level | 200  |
| shipped in | ambient |
| SMILES string | [Na+].CCCCCCCCCCCCCCCC([O |
| storage temp. | 2-8°C |
| Application: | Sodium palmitate (PA) has been used: • to induce inflammation and thrombosis pathway in murine macrophage cell line RAW 264.7 cell line by activating reactive oxygen species (ROS) production, Janus-kinase (JNK) signalling and release of histone H3 by western blotting and cell viability by MTT assay • to induce lipogenesis in AML12 cells and primary hepatocytes to analyse the effect of irisin on PA induced lipogenesis and related signal pathways by western blot analysis and quantitative PCR analysis • as a component in free fatty acid mixture to induce cellular steatosis in HepG2 cell lines and determination of lipid accumulation by Oil-Red-O staining |
| Biochem/physiol Actions: | Sodium palmitate is the sodium salt of palmitic acid, a component in hard soaps. Palmitic acid is a common saturated fatty acid and produced during fatty acid synthesis. Sodium palmitate enhances lipogenesis, cellular steatosis in various cell lines. Palmitate induces cell death in human epidermal growth factor receptor 2 (HER2)/neu-positive cells and breast cancer cell lines like MCF-7 due to enhanced fatty acid accumulation. Sodium palmitate induces lipoapoptosis in L02 and HepG2 liver cells by inducing glycogen synthase kinase-3β (GSK3β) expression. |
| Packaging: | 5, 10, 50 g in poly bottle |
| Hazard Codes | Xi |
| Risk Statements | 36 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.5% |
| mp | 283-290 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352211 |