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PTP-β human

SIGMA/P9864 - ≥90%, recombinant, expressed in E. coli K12, GST-tagged, buffered aqueous glycerol solution, ≥50,000 units/mg protein

Synonym: Protein Tyrosine Phosphatase-β

CAS Number: 300853-81-0
MDL Number: MFCD02688688
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-P9864-10000UN 10000 units
$731.00
1/EA
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application(s) cell analysis
assay ≥90%
biological source human
form buffered aqueous glycerol solution
mol wt ~250 kDa
Quality Level 200 
recombinant expressed in E. coli K12
shipped in dry ice
specific activity ≥50,000 units/mg protein
storage temp. −70°C
UniProt accession no. P23467 
Biochem/physiol Actions: Dephosphorylates tyrosine proteins.
General description: Protein tyrosine phosphatase, receptor type B (PTPRB), also known as vascular endothelial-protein-tyrosine phosphatase (VE-PTP), might have a role in remodeling of blood vessels and in angiogenesis. The gene encoding it is localized on human chromosome 12q15. It is also important for endothelial cell migration. The protein also controls the phosphorylation state of the angiopoietin receptor, Tie-2. PTPRB may modulate sodium channels by influencing the tyrosine phosphorylation status.
Other Notes: One unit of PTP-β will hydrolyze 1.0 nanomole of p-nitrophenyl phosphate per min at 30 °C.
Physical form: solution in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCL, 3 mM DTT, 16 mM glutathione and 20% glycerol
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥90%
activity specific activity: ≥50,000 units/mg protein
Storage Temp. −70°C
UNSPSC 12352200

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