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Penicillin G sodium salt

SIGMA/PENNA - ~1650 U/mg

Synonym: Benzylpenicillin sodium salt

CAS Number: 69-57-8
Empirical Formula (Hill Notation): C16H17N2NaO4S
Molecular Weight: 356.37
EC Number: 200-710-2
MDL Number: MFCD00069666
Linear Formula: C16H17N2NaO4S
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-PENNA-1MU 1000000 units
$29.60
1/EA
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45-PENNA-10MU 10000000 units
$38.00
1/EA
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45-PENNA-100MU 100000000 units
$193.00
1/EA
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antibiotic activity spectrum Gram-negative bacteria
  Gram-positive bacteria
form powder
InChI 1S/C16H18N2O4S.Na/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1
InChI key FCPVYOBCFFNJFS-LQDWTQKMSA-M
mode of action cell wall synthesis | interferes
Quality Level 200 
SMILES string [Na+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O
solubility H2O: 100 mg/mL
specific activity ~1650 U/mg
storage temp. 2-8°C
Application: Penicillin G sodium salt has been used:
•  to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility
•  in cell culture alone as well as in combination with streptomycin and other antibiotics
•  to inhibit the synthesis of bacterial cell walls by inhibition of the cell wall peptidoglycan chain cross-lining
Biochem/physiol Actions: Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking.

Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.
Disclaimer: Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The sodium salt is soluble in H2O at 100 mg/mL.
General description: Penicillin G is a narrow spectrum antibiotic. It is effective against Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. Penicillin G contains β-lactam ring in their chemical structure.
Other Notes: Keep container tightly closed in a dry and well-ventilated place.Product contains Penicillin
Packaging: 1mu,10mu,100mu
activity specific activity: ~1650 U/mg
Storage Temp. 2-8°C
UNSPSC 51283424

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