Rabbit anti-WAPL Antibody, Affinity Purified
SIGMA/PLA0076 - Powered by Bethyl Laboratories, Inc.
Synonym: FOE; KIAA0261; WAPAL; WAPL cohesin release factor; friend of EBNA2; friend of EBNA2 (Epstein-Barr virus nuclear protein 2); friend of EBNA2 protein; wings apart-like homolog (Drosophila)
Product Type: Product-on-demand
Western Blotting Rabbit Anti-WAPL Antibody, Affinity Purified: Cat. No. PLA0076: Detection of Human WAPL by Western Blot. Sample: Nuclear extract (NE) from HeLa cells. Antibody: Affinity purified Rabbit Anti-WAPL Antibody (Cat. No. PLA0076) used at 0.2 μg/mL. Detection: Chemiluminescence with an exposure time of 20 minutes.
| accession no. | Q7Z5K2 |
| antibody form | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1:10,000-1:25,000 |
| UniProt accession no. | Q7Z5K2  |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | The epitope recognized by PLA0076 maps to a region between residues 1125 and 1175 of human wings apart like/KIAA0261 using the numbering given in TrEMBL entry Q7Z5K2 (GeneID 23063). |
| Other Notes: | Wings apart-like protein homolog (WAPL) is a cohesin binding protein that functions to destabilize cohesin-linked sister chromatids during prophase. Human WAPL has been shown to be highly expressed in cervical cancer and when over-expressed in mouse cells, induces tumorigenesis. WAPL was isolated in a screen for proteins that interact with Epstein-Barr nuclear protein 2 (EBNA2). |
| Physical form: | Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |