Rabbit anti-FANCE Antibody, Affinity Purified
SIGMA/PLA0240 - Powered by Bethyl Laboratories, Inc.
Synonym: FACE; FAE; Fanconi anemia; Protein FACE; complementation group E
Product Type: Product-on-demand
Western Blotting Rabbit Anti-FANCE Antibody, Affinity Purified: Cat. No. PLA0240: Detection of Human FANCE by Western Blot. Samples: Whole cell lysate (5, 15 and 50 μg) from HeLa cells. Antibodies: Affinity purified Rabbit Anti-FANCE antibody Cat. No. PLA0240 used for WB at 0.1 μg/mL. Detection: Chemiluminescence with exposure time of 10 seconds.
Immunoprecipitation Rabbit Anti-FANCE Antibody, Affinity Purified: Cat. No. PLA0240: Detection of Human FANCE by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified Rabbit Anti-FANCE antibody Cat. No. PLA0240 used for WB at 1 μg/mL and for IP at 10 μg/mg lysate. FANCE was also immunoprecipitated by Rabbit Anti-FANCE Antibody B, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure time of 10 seconds.
| accession no. | NP_068741.1 |
| antibody form | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| technique(s) | immunoprecipitation (IP): 5-10 μg/mg |
| western blot: 1:2,000- 1:10,000 | |
| UniProt accession no. | Q9HB96  |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | The epitope recognized by PLA0240 maps to a region between residue 200 and 250 of human Fanconi anemia, complementation group E using the numbering given in entry NP_068741.1 (GeneID 2178). |
| Other Notes: | FANCE (Fanconi anemia, complementation group E) is a protein involved in DNA repair. Defects in FANCE are the cause of Fanconi anemia, a heterogenous autosomal recessive disorder characterized by congenital malformations and a predisposition to cancer. The FANCE gene is one of 13 complementation groups that include FANCA, FANCB, FANCC, FANCD1/BRCA2, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ/BRIP1, FANCL, FANCM, and FANCN/PALB2. FANCE has been shown to mediate the interaction between FANCC and FANCD2. |
| Physical form: | Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |