Anti-BAFF antibody produced in rabbit
SIGMA/PRS2221 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-BLyS; Anti-Tall; Anti-Thank; Anti-Tumor necrosis factor (ligand) superfamily, member 13b
MDL Number: MFCD02265860
Product Type: Chemical
Immunocytochemistry Anti-BAFF: Cat. No. PRS2221 Immunocytochemistry of BAFF in HL60 cells with BAFF antibody at 1 μg/mL.
Immunofluorescence Immunofluorescence of BAFF in human spleen tissue with BAFF antibody at 20 μg/mL.
Immunoblotting Anti-BAFF: Cat. No. PRS2221 Western blot analysis of BAFF in human HL60 cell lysate (H) and mouse spleen tissue lysate (M) with BAFF antibody at 1 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | predicted mol wt 31 kDa |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | human, rat, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunocytochemistry: suitable |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | Q9Y275  |
| Biochem/physiol Actions: | B cell activating factor (BAFF) participates in B cell and T cell mediated immunity. It plays a key role in the survival and differentiation of B cells. Mutations in BAFF regulates the levels of antibody. BAFF also participates in enhancing the responses of IL-6 (interlukin-6) and TNF-α (tumor necrosis factor alpha), that helps hepatocytes in the production of acute-phase protein. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | B-lymphocyte activating factor (BAFF/TNFSF13B) is a cytokine that belongs to the TNF (tumor necrosis factor) superfamily. BAFF is located on human chromosome 13q33. |
| Immunogen: | a peptide corresponding to amino acids near the carboxy-terminus of human BAFF. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP2221 . |
| Physical form: | Solution in phosphate buffered saline containing 0.02% sodium azide |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |