Anti-TLR4 antibody produced in rabbit
SIGMA/PRS3141 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-Toll-like receptor 4
MDL Number: MFCD03455299
Product Type: Chemical
Immunocytochemistry Anti-TLR4: Cat. No. PRS3141 Immunocytochemistry of TLR4 in K562 cells with TLR4 antibody at 2 μg/mL.
Immunohistochemistry Immunohistochemistry of TLR4 in human spleen tissue with TLR4 antibody at 2.5 μg/mL.
Immunofluorescence Immunofluorescence of TLR4 in human spleen tissue with TLR4 antibody at 20 μg/mL.
Immunoblotting Anti-TLR4: Cat. No. PRS3141 Western blot analysis of TLR4 in PC-3 cell lysates with TLR4 antibody at (A) 2.5 and (B) 5 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | predicted mol wt 92 kDa |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunocytochemistry: suitable |
| immunofluorescence: suitable | |
| immunohistochemistry: suitable | |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | O00206  |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Toll-like receptors (TLRs) are transmembrane receptors expressed on the surface of immune and non-immune cells. There are at least 13 different TLRs identified that mediate signalling pathways contributing to acute inflammatory processes during tissue damage and bacterial infections TLR2 is highly inducible by numerous inflammatory mediators resulting in translocation of transcription factor NF-κB-mediated proinflammatory cytokines and immune responses |
| Immunogen: | a peptide corresponding to 15 amino acids near the amino-terminus of human TLR4. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3141 . |
| Physical form: | Solution in phosphate buffered saline containing 0.02% sodium azide |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |