Anti-XIAP antibody produced in rabbit
SIGMA/PRS3331 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-X-linked inhibitor of apoptosis
MDL Number: MFCD01633419
Product Type: Chemical
Immunohistochemistry Anti-XIAP: Cat. No. PRS3331 Immunohistochemical staining of human kidney tissue using XIAP antibody at 2 μg/mL.
Immunohistochemistry Immunohistochemistry of XIAP in mouse kidney tissue with XIAP antibody at 5 μg/mL.
Immunofluorescence Immunofluorescence of XIAP in Human Kidney tissue with XIAP antibody at 10 μg/mL.
Immunoblotting Anti-XIAP: Cat. No. PRS3331 Western blot analysis of XIAP in human kidney lysate with XIAP antibody at 0.5 (Lane A), 1 (Lane B), and 2 (Lane C) μg/mL, respectively.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | predicted mol wt 55 kDa |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| immunohistochemistry: suitable | |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | P98170  |
| Application: | Anti-XIAP has been used in immunohistochemistry {16,17}. |
| Biochem/physiol Actions: | XIAP (X-linked inhibitor of apoptosis protein) modulates several cellular processes like TGF-β (transforming growth factor β) signaling, NF-κB (nuclear factor-κB) pathway, autophagy and inflammatory responses. XIAP mutations are associated with X-linked lymphoproliferative syndrome type 2 (XLP-2). |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | XIAP (X-linked inhibitor of apoptosis protein) belongs to the inhibitor of apoptosis (IAP) family. It is located on chromosome Xq25. |
| Immunogen: | a synthetic peptide corresponding to 13 amino acids at the C-terminus of human XIAP. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3331 . |
| Physical form: | Solution in phosphate buffered saline containing 0.02% sodium azide |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |