Anti-Sumo antibody produced in rabbit
SIGMA/PRS3969 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-GAP-modifying protein 1; Anti-SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae); Anti-Ubiquitin-like protein 1; Anti-
MDL Number: MFCD02096449
Product Type: Chemical
Immunocytochemistry Anti-Sumo: Cat. No. PRS3969 Immunocytochemistry of Sumo in HL60 cells with Sumo antibody at 5 μg/mL.
Immunofluorescence Immunofluorescence of Sumo in HL60 cells with Sumo antibody at 20 μg/mL.
Immunoblotting Anti-Sumo: Cat. No. PRS3969 Western blot analysis of sumo in HL-60 cell lysate with sumo antibody at (A) 0.5, (B) 1, and (C) 2 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | mouse, human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| immunohistochemistry: suitable | |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | P63165  |
| Biochem/physiol Actions: | Suppressing SUMO1 (small ubiquitin-related modifier) stops multiplication and induces apoptosis of gastric cancer SGC-7901 cells. It is essential for HCV (hepatitis C virus) replication. Deletion of SUMO1 blocks the aggregation of lipid droplets. It involves in mitochondrial fission. |
| Biochem/physiol Actions: | Suppressing SUMO1 (small ubiquitin-related modifier) stops multiplication and induces apoptosis of gastric cancer SGC-7901 cells. It is essential for HCV (hepatitis C virus) replication. Deletion of SUMO1 blocks the aggregation of lipid droplets. It is involved in mitochondrial fission. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | SUMO1 (small ubiquitin-related modifier) is also called as Pic1 (inner centromere protein-related protein), Ubl1 (ubiquitin-like protein), hSmt3 (human homolog 3), or sentrin. It is located in the nucleus. SUMO1 gene is located on human chromosome 2q33. |
| Immunogen: | a 14 amino acid peptide from near the amino-terminus of human sumo. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3969 . |
| Physical form: | Solution in phosphate buffered saline containing 0.02% sodium azide |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |