Anti-APH1 (ab2) antibody produced in rabbit
SIGMA/PRS4003 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-Anterior pharynx defective 1 homolog A (C. elegans); Anti-Presenilin stabilization factor
Product Type: Chemical
Immunohistochemistry Anti-APH1: Cat. No. PRS4003 Immunohistochemistry of APH1 in human brain tissue with APH1 antibody at 5 μg/mL.
Immunoblotting Anti-APH1: Cat. No. PRS4003 Western blot analysis of APH1 in human brain tissue lysate with APH1 antibody at (A) 0.5 and (B) 1 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | predicted mol wt 29 kDa |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | mouse, human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | Q96BI3  |
| Biochem/physiol Actions: | APH1 (anterior pharynx defective-1) participates in the secretase like activity. Throughout the embryonic development, APH1 participates in presenilin dependent function. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | APH1 (anterior pharynx defective-1) is a component of γ-secretase complex. It is located on chromosome 1q21. It has 2 unique isoforms such as APH1a, located on chromosome 1 and APH1b, located on chromosome 15 (3). |
| Immunogen: | a 18 amino acid peptide from near the center of human APH1. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP4003 . |
| Physical form: | Solution in phosphate buffered saline containing 0.02% sodium azide |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |