Anti-ZBP1 antibody produced in rabbit
SIGMA/PRS4401 - affinity isolated antibody, buffered aqueous solution
Synonym: ZBP1 Antibody - Anti-ZBP1 antibody produced in rabbit; Zbp1 Antibody; Anti-DAI; Anti-DLM-1; Anti-Z-DNA binding protein 1
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of ZBP1 in human small intestine tissue with ZBP1 antibody at 2.5 μg/mL.
Immunofluorescence Immunofluorescence of ZBP1 in Human Small Intestine tissue with ZBP1 antibody at 20 μgg/mL.
Immunoblotting Anti-ZBP1: Cat. No. PRS4401 Western blot analysis of ZBP1 in mouse small intestine tissue lysate with ZBP1 antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | predicted mol wt 39-45 kDa |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | human, rat, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| immunohistochemistry: suitable | |
| indirect ELISA: suitable | |
| western blot: suitable | |
| UniProt accession no. | Q9H171  |
| Application: | Anti-ZBP1 antibody produced in rabbit has been used for western blotting. |
| Biochem/physiol Actions: | Z-DNA binding protein 1 (ZBP1) plays a major role in DNA mediated innate immune responses. It enhances nuclear factor k-light-chain-enhancer of activated B cells (NFκB) activation and proinflammatory cytokine production. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Z-DNA binding protein 1 (ZBP1), also known as interferon (IFN) γ-inducible gene, is a cytoplasmic DNA sensor. It belongs to the family of Z-DNA binding proteins. ZBP1 is majorly expressed in the small intestine and lymphatic tissues. The gene is located on human chromosome 20q13.3. |
| Immunogen: | a 18 amino acid peptide from near the carboxy-terminus of human ZBP1. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP4401 . |
| Physical form: | Solution in phosphate buffered saline containing 0.02% sodium azide |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |