Anti-IL-17 (ab1) antibody produced in rabbit
SIGMA/PRS4877 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-CTLA8; Anti-Interleukin 17A
Product Type: Chemical
Immunoblotting Anti-IL-17: Cat. No. PRS4877 Western blot analysis of IL-17 in A-20 lysate with IL-17 antibody at (A) 2 and (B) 4 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | predicted mol wt 17 kDa |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: suitable | |
| UniProt accession no. | Q16552  |
| Application: | Anti-IL-17 has been used in western blotting and immunohistochemistry. |
| Biochem/physiol Actions: | IL-17A (interleukin 17A) plays a major role in the pathogenesis of autoimmune diseases like multiple sclerosis and rheumatoid arthritis. It also plays a pathogenic role in allergic rhinitis (AR). It helps in the formation of several chemokines and cytokines in airway epithelial cells. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | IL-17A (interleukin 17A) is a proinflammatory cytokine of Th17 (helper T cells). It is located on chromosome 6p12. |
| Immunogen: | a 16 amino acid peptide from near the amino-terminus of human IL-17A. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP4877 . |
| Physical form: | Solution in phosphate buffered saline containing 0.02% sodium azide |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |