Exemestane

SIGMA/PZ0006 - ≥98% (HPLC)

Synonym: 6-Methyleneandrosta-1,4-diene-3,17-dione

CAS Number: 107868-30-4
Empirical Formula (Hill Notation): C₂₀H₂₄O₂
Molecular Weight: 296.40
MDL Number: MFCD00866994
Linear Formula: C₂₀H₂₄O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-PZ0006-5MG	5 mg	$148.00 1/EA		Add To Favorites
45-PZ0006-25MG	25 mg	$601.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to off-white
form	powder
InChI	1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1
InChI key	BFYIZQONLCFLEV-DAELLWKTSA-N
optical activity	[α]/D +250 to +300°, c = 1 in methanol
Quality Level	100
SMILES string	C[C@]12CC[C@H]3[C@@H](CC(=C)C4=CC(=O)C=C[C@]34C)[C@@H]1CCC2=O
solubility	DMSO: ≥20 mg/mL
storage temp.	2-8°C

Biochem/physiol Actions:	Exemestane is a steroidal antiestrogen and irreversible aromatase inhibitor. Exemestane acts as a false substrate for the aromatase enzyme. Exemestane also prevents the conversion of androgens to estrogens and is used to treat estrogen-dependent breast cancer.
Biochem/physiol Actions:	Exemestane is a steroidal antiestrogen; aromatase inhibitor.
Features and Benefits:	This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging:	5, 25 mg in glass bottle

Symbol	GHS08,GHS09
Signal word	Danger
Hazard statements	H360 - H411
Precautionary statements	P201 - P202 - P273 - P280 - P308 + P313 - P391
Hazard Codes	T,N
Risk Statements	60-61-51
Safety Statements	53-22-36/37-57
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	51111800

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