Trovafloxacin mesylate

SIGMA/PZ0015 - >98% (HPLC)

Synonym: (1α,5α,6α)-7-(6-Amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid methanesulfonate; CP-99219-27; Trovafloxacin methanesulfonate

CAS Number: 147059-75-4
Empirical Formula (Hill Notation): C₂₀H₁₅F₃N₄O₃ · CH₃SO₃H
Molecular Weight: 512.46
MDL Number: MFCD00913361
Linear Formula: C₂₀H₁₅F₃N₄O₃ · CH₃SO₃H
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-PZ0015-25MG	25 mg	$518.00 1/EA	Add To Favorites

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This image depicts PZ0015-5MG.

Properties
Descriptions
Safety Info.
Basic Data

assay	>98% (HPLC)
color	white to off-white
form	powder
InChI	1S/C20H15F3N4O3.CH4O3S/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24;1-5(2,3)4/h1-4,7,10-11,16H,5-6,24H2,(H,29,30);1H3,(H,2,3,4)/t10-,11+,16+;
InChI key	DYNZICQDCVYXFW-AHZSKCOESA-N
Quality Level	100
SMILES string	CS(O)(=O)=O.NC1C2CN(CC12)c3nc4N(C=C(C(O)=O)C(=O)c4cc3F)c5ccc(F)cc5F
solubility	DMSO: >10 mg/mL
storage temp.	room temp

Application:	Trovafloxacin mesylate has been used as a test compound in toxicity assay to assess its toxicity in 2D hepatocyte cultures. It has also been used to manipulate the mechanism of apoptotic cell disassembly during apoptosis.
Biochem/physiol Actions:	Trovafloxacin mesylate acts as a pannexin1 (Panx1) inhibitor.
Biochem/physiol Actions:	Trovafloxacin mesylate is a broad spectrum antibiotic.
Biochem/physiol Actions:	Trovafloxacin mesylate is a broad spectrum antibiotic. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA.
Packaging:	5, 25 mg in glass bottle

Symbol	GHS05,GHS08
Signal word	Danger
Hazard statements	H314 - H361
Precautionary statements	P201 - P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338
Hazard Codes	C
Risk Statements	63-34
Safety Statements	26-36-45
RIDADR	UN 1759 8 / PGIII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	>98% (HPLC)
Storage Temp.	room temp
UNSPSC	12352200

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