Synonym: (1α,5α,6α)-7-(6-Amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid methanesulfonate; CP-99219-27; Trovafloxacin methanesulfonate
CAS Number: 147059-75-4
Empirical Formula (Hill Notation): C20H15F3N4O3 · CH3SO3H
Molecular Weight: 512.46
MDL Number: MFCD00913361
Linear Formula: C20H15F3N4O3 · CH3SO3H
Product Type: Chemical
| assay |
>98% (HPLC) |
| color |
white to off-white |
| form |
powder |
| InChI |
1S/C20H15F3N4O3.CH4O3S/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24;1-5(2,3)4/h1-4,7,10-11,16H,5-6,24H2,(H,29,30);1H3,(H,2,3,4)/t10-,11+,16+; |
| InChI key |
DYNZICQDCVYXFW-AHZSKCOESA-N |
| Quality Level |
100  |
| SMILES string |
CS(O)(=O)=O.NC1C2CN(CC12)c3nc4N(C=C(C(O)=O)C(=O)c4cc3F)c5ccc(F)cc5F |
| solubility |
DMSO: >10 mg/mL |
| storage temp. |
room temp |
| Application: |
Trovafloxacin mesylate has been used as a test compound in toxicity assay to assess its toxicity in 2D hepatocyte cultures. It has also been used to manipulate the mechanism of apoptotic cell disassembly during apoptosis. |
| Biochem/physiol Actions: |
Trovafloxacin mesylate acts as a pannexin1 (Panx1) inhibitor. |
| Biochem/physiol Actions: |
Trovafloxacin mesylate is a broad spectrum antibiotic. |
| Biochem/physiol Actions: |
Trovafloxacin mesylate is a broad spectrum antibiotic. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA. |
| Packaging: |
5, 25 mg in glass bottle |
| Purity |
>98% (HPLC) |
| Storage Temp. |
room temp |
| UNSPSC |
12352200 |
GHS05,GHS08