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Rucaparib camsylate

SIGMA/PZ0036 - ≥98% (HPLC)

Synonym: 8-fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-Pyrrolo[4,3,2-ef][2]benzazepin-6-one camsylate

CAS Number: 1859053-21-6
Empirical Formula (Hill Notation): C19H18FN3O · C10H16O4S
Molecular Weight: 555.66
Linear Formula: C19H18FN3O · C10H16O4S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-PZ0036-5MG 5 mg
 $116.00
1/EA		 Add To Favorites
45-PZ0036-25MG 25 mg
 $467.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts PZ0036-25MG.

 

assay ≥98% (HPLC)
color pale yellow
form powder
InChI 1S/C19H18FN3O.C10H16O4S/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15;1-9(2)7-3-4-10(9,8(11)5-7)6-15(12,13)14/h2-5,8-9,21,23H,6-7,10H2,1H3,(H,22,24);7H,3-6H2,1-2H3,(H,12,13,14)/t;7-,10-/m.1/s1
InChI key INBJJAFXHQQSRW-STOWLHSFSA-N
shipped in dry ice
SMILES string FC1=CC(C(NCC2)=O)=C3C2=C(C4=CC=C(CNC)C=C4)NC3=C1.CC5(C)[C@@H]6CC[C@@]5(CS(O)(=O)=O)C(C6)=O
solubility DMSO: 2 mg/mL, clear
storage temp. −20°C
Biochem/physiol Actions: PARP Inhibitor; anticancer agent
Biochem/physiol Actions: Rucaparib is an inhibitor of the DNA repair enzyme poly-ADP ribose polymerase-1 (PARP-1). It has been found to have anticancer activity in a number of cancers and has been approved for treatment of previously treated, BRCA-mutant ovarian cancer.
Symbol GHS08  GHS08
Signal word Warning
Hazard statements H361
Precautionary statements P280
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352202

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