PD-407824

SIGMA/PZ0111 - ≥98% (HPLC)

Synonym: 9-Hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione

CAS Number: 622864-54-4
Empirical Formula (Hill Notation): C₂₀H₁₂N₂O₃
Molecular Weight: 328.32
MDL Number: MFCD09753286
Linear Formula: C₂₀H₁₂N₂O₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-PZ0111-25MG	25 mg	$635.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	yellow to orange
form	powder
InChI	1S/C20H12N2O3/c23-11-6-7-14-13(8-11)16-15(21-14)9-12(10-4-2-1-3-5-10)17-18(16)20(25)22-19(17)24/h1-9,21,23H,(H,22,24,25)
InChI key	IAUZTOZLTFSMIE-UHFFFAOYSA-N
Quality Level	100
SMILES string	Oc1ccc2[nH]c3cc(-c4ccccc4)c5C(=O)NC(=O)c5c3c2c1
solubility	DMSO: >10 mg/mL
storage temp.	2-8°C

Application:	PD-407824 has been used as a wee-1 inhibitor to study its effects on Xenopus laevis embryos. It has also been used as a checkpoint-1 (Chk-1) inhibitor to study its effects on the sensitivity of head and neck squamous carcinoma cells to gemcitabine.
Biochem/physiol Actions:	PD-407824 is a Wee1/Chk1 inhibitor.
Packaging:	5, 25 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P261 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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