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PF-04418948

SIGMA/PZ0213 - ≥98% (HPLC)

Synonym: 1-(4-Fluorobenzoyl)-3-[[(6-methoxy-2-naphthalenyl)oxy]methyl]-3-azetidinecarboxylic acid

CAS Number: 1078166-57-0
Empirical Formula (Hill Notation): C23H20FNO5
Molecular Weight: 409.41
Linear Formula: C23H20FNO5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-PZ0213-25MG 25 mg
 $528.00
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This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C23H20FNO5/c1-29-19-8-4-17-11-20(9-5-16(17)10-19)30-14-23(22(27)28)12-25(13-23)21(26)15-2-6-18(24)7-3-15/h2-11H,12-14H2,1H3,(H,27,28)
InChI key LWJGMYMNSNVCEM-UHFFFAOYSA-N
Quality Level 100 
SMILES string Fc1ccc(cc1)C(=O)N2CC(C2)(COc3cc4c(cc(cc4)OC)cc3)C(=O)O
solubility DMSO: 20 mg/mL, clear
storage temp. room temp
Application: PF-04418948 has been used in TG (trigeminal ganglion) explant culture.
Biochem/physiol Actions: PF-04418948 is a PGE2 Receptor (EP2) specific antagonist (IC50 = 16 nM) with greater than 2000-fold selectivity over other EP subtypes. PF-04418948 inhibits EP2 activity in smooth muscle preps from human, dog and mouse.
Biochem/physiol Actions: PF-04418948 is a PGE2 Receptor (EP2) specific antagonist.
Biochem/physiol Actions: PF-04418948 represses the formation of colorectal tumor.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352200

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