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PF-06733804

SIGMA/PZ0341 - ≥98% (HPLC)

Synonym: 6-Amino-5-((1S)-2,2-difluoro-4-(2-(4-(trifluoromethoxy)phenyl)acetyl)cyclopentyloxy)-N-methylnicotinamide; 6-Amino-5-[[(3S)-4,4-difluoro-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]-3-pyrrolidinyl]oxy]-N-methyl-3-pyridinecarboxamide; PF06733804

CAS Number: 1873373-33-1
Empirical Formula (Hill Notation): C20H19F5N4O4
Molecular Weight: 474.38
Linear Formula: C20H19F5N4O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-PZ0341-5MG 5 mg
 $72.80
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C20H19F5N4O4/c1-27-18(31)12-7-14(17(26)28-8-12)32-15-9-29(10-19(15,21)22)16(30)6-11-2-4-13(5-3-11)33-20(23,24)25/h2-5,7-8,15H,6,9-10H2,1H3,(H2,26,28)(H,27,31)/t15-/m0/s1
InChI key FTAFQADCGCSJAH-HNNXBMFYSA-N
Quality Level 100 
SMILES string NC1=C(O[C@H]2CN(C(CC3=CC=C(OC(F)(F)F)C=C3)=O)CC2(F)F)C=C(C(NC)=O)C=N1
solubility DMSO: 20 mg/mL, clear
storage temp. room temp
Biochem/physiol Actions: PF-06733804 is pan tropomyosin-related kinase (Trk) inhibitor.
Biochem/physiol Actions: PF-06733804 is pan tropomyosin-related kinase inhibitor.
Packaging: 5, 25 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H315 - H319 - H335
Precautionary statements P305 + P351 + P338
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352200

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