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Quinine hydrochloride dihydrate

SIGMA/Q1125

CAS Number: 6119-47-7
Empirical Formula (Hill Notation): C20H24N2O2 · HCl · 2H2O
Molecular Weight: 396.91
EC Number: 205-001-1
MDL Number: MFCD00078498
Linear Formula: C20H24N2O2 · HCl · 2H2O
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-Q1125-5G 5 g
$68.70
1/EA
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45-Q1125-10G 10 g
$127.00
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45-Q1125-25G 25 g
$232.00
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45-Q1125-50G 50 g
$519.00
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45-Q1125-100G 100 g
$700.00
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antibiotic activity spectrum parasites
InChI 1S/C20H24N2O2.ClH.H2O/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;;/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;1H;1H2/t13-,14-,19-,20+;;/m0../s1
InChI key SGVZDMWHXVXUBY-HZQSTTLBSA-N
mode of action enzyme | inhibits
Quality Level 200 
SMILES string O.Cl.[H][C@]1(C[C@@H]2CC[N@H]1C[C@@H]2C=C)[C@H](O)c3ccnc4ccc(OC)cc34
solubility H2O: 0.25/5 g/mL, clear, colorless
Application: Quinine hydrochloride dihydrate has been used in Drosophila larval behavioral assay. It has also been used in taste preference analysis among rats.
Biochem/physiol Actions: Potassium channel blocker
Biochem/physiol Actions: Quinine is widely used in the treatment of malaria. It possesses erythrocytic and gametocytocidal action against Plasmodium sp. It also serves as an analgesic drug. Upon administration, quinine is present mostly bound to α-1 acid glycoprotein in the body fluids. Quinine has the ability to cross the placenta and the blood brain barrier. It has a half-life of 11-18 hours. Tinnitus, hearing defects, nausea and headache are some of its side effects.
General description: Quinine is derived from the stem of cinchona (quina-quina) tree. It is an alkaloid having various applications in the field of medicine. Quinine is a basic compound with aryl amino alcohol group.
UNSPSC 12352210

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