Quinine hydrochloride dihydrate
SIGMA/Q1125
CAS Number: 6119-47-7
Empirical Formula (Hill Notation): C20H24N2O2 · HCl · 2H2O
Molecular Weight: 396.91
EC Number: 205-001-1
MDL Number: MFCD00078498
Linear Formula: C20H24N2O2 · HCl · 2H2O
Product Type: Chemical
| antibiotic activity spectrum | parasites |
| InChI | 1S/C20H24N2O2.ClH.H2O/c1- |
| InChI key | SGVZDMWHXVXUBY-HZQSTTLBSA |
| mode of action | enzyme | inhibits |
| Quality Level | 200 ![]() |
| SMILES string | O.Cl.[H][C@]1(C[C@@H]2CC[ |
| solubility | H2O: 0.25/5 g/mL, clear, colorless |
| Application: | Quinine hydrochloride dihydrate has been used in Drosophila larval behavioral assay. It has also been used in taste preference analysis among rats. |
| Biochem/physiol Actions: | Potassium channel blocker |
| Biochem/physiol Actions: | Quinine is widely used in the treatment of malaria. It possesses erythrocytic and gametocytocidal action against Plasmodium sp. It also serves as an analgesic drug. Upon administration, quinine is present mostly bound to α-1 acid glycoprotein in the body fluids. Quinine has the ability to cross the placenta and the blood brain barrier. It has a half-life of 11-18 hours. Tinnitus, hearing defects, nausea and headache are some of its side effects. |
| General description: | Quinine is derived from the stem of cinchona (quina-quina) tree. It is an alkaloid having various applications in the field of medicine. Quinine is a basic compound with aryl amino alcohol group. |
| Symbol | ![]() GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H302 - H317 - H334 |
| Precautionary statements | P261 - P264 - P270 - P280 - P301 + P312 - P302 + P352 |
| Hazard Codes | Xn |
| Risk Statements | 22-42/43 |
| Safety Statements | 22-36/37-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12352210 |



