Quinine hemisulfate salt monohydrate

SIGMA/Q1250 - synthetic, ≥90% (HPLC)

CAS Number: 207671-44-1
Empirical Formula (Hill Notation): C₂₀H₂₄N₂O₂ · 0.5H₂O₄S · H₂O
Molecular Weight: 391.47
MDL Number: MFCD00150790
Linear Formula: C₂₀H₂₄N₂O₂ · 0.5H₂O₄S · H₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-Q1250-5G	5 g	$36.90 1/EA	Add To Favorites
45-Q1250-10G	10 g	$56.60 1/EA	Add To Favorites
45-Q1250-50G	50 g	$196.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	parasites
assay	≥90% (HPLC)
biological source	synthetic
InChI	1S/2C20H24N2O2.H2O4S.2H2O/c21-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h23-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);21H2/t213-,14-,19-,20+;;;/m00.../s1
InChI key	ZHNFLHYOFXQIOW-LPYZJUEESA-N
mode of action	enzyme \| inhibits
mp	~225 °C (dec.) (lit.)
originator	Bayer
Quality Level	200
SMILES string	O.O.OS(O)(=O)=O.COc1ccc2nccc([C@@H](O)C3CC4CCN3C[C@@H]4C=C)c2c1.COc5ccc6nccc([C@@H](O)C7CC8CCN7C[C@@H]8C=C)c6c5
solubility	ethanol: 8 mg/mL
	H₂O: slightly soluble 1.2 mg/mL

Application:	Quinine hemisulfate salt monohydrate has been used as a stimuli to evaluate its influence on sensory and cognitive factors.
Biochem/physiol Actions:	Potassium channel blocker. Antimalarial
Biochem/physiol Actions:	Potassium channel blocker. Antimalarial, anticholinergic, antihypertensive, and hypoglycemic agent; alkaloid originally isolated from the Cinchona family of South American trees. Inhibits mitochondrial ATP-regulated potassium channel. Used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.
Biochem/physiol Actions:	Quinine has analgesic property.
Features and Benefits:	This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits:	This compound was developed by Bayer . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging:	5, 10, 50 g in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥90% (HPLC)
mp	~225 °C (dec.) (lit.)
UNSPSC	12352210

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