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Quinacrine mustard dihydrochloride

SIGMA/Q2876 - ≥85% (HPLC)

Synonym: 2-Methoxy-6-chloro-9-(4-bis[β-chloroethyl]amino-1-methylbutylamino)acridine dihydrochloride; 9-[4-(Bis(2-chloroethyl)amino)-1-methylbutylamino]-6-chloro-2-methoxyacridine dihydrochloride

CAS Number: 4213-45-0
Empirical Formula (Hill Notation): C23H28Cl3N3O · 2HCl
Molecular Weight: 541.77
EC Number: 224-140-9
MDL Number: MFCD00043254
Linear Formula: C23H28Cl3N3O · 2HCl
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-Q2876-5MG 5 mg
$114.00
1/EA
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45-Q2876-25MG 25 mg
$309.00
1/EA
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45-Q2876-100MG 100 mg
$916.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: Q2876-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: Q2876-5MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: Q2876-25MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: Q2876-5MG

 

assay ≥85% (HPLC)
InChI 1S/C23H28Cl3N3O.2ClH/c1-16(4-3-11-29(12-9-24)13-10-25)27-23-19-7-5-17(26)14-22(19)28-21-8-6-18(30-2)15-20(21)23;;/h5-8,14-16H,3-4,9-13H2,1-2H3,(H,27,28);2*1H
InChI key JETDZFFCRPFPDH-UHFFFAOYSA-N
Quality Level 200 
SMILES string Cl[H].Cl[H].COc1ccc2nc3cc(Cl)ccc3c(NC(C)CCCN(CCCl)CCCl)c2c1
storage temp. −20°C
Application: Quinacrine mustard dihydrochloride is used to stain metaphase chromosomes. Recent applications include the Q-banding of maize and karyotyping of fish. The dye is also used as a vital stain for trypanosomes.
General description: Quinacrine mustard dihydrochloride is a fluorescent acridine dye, also abbreviated as QM. In an aqueous solution, the chloroethyl groups rapidly lose chloride ions yielding aziridinium cations. These readily react with the carboxyl, thiol, and heterocyclic ring nitrogen groups of proteins and nucleic acids, or with other nucleophiles.
Packaging: 100 mg in glass bottle
Packaging: 25 mg in poly bottle
Packaging: 5 mg in glass bottle
Purity ≥85% (HPLC)
Storage Temp. −20°C
UNSPSC 12352101

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