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Quinacrine dihydrochloride

SIGMA/Q3251 - ≥90%

Synonym: 6-Chloro-9-(4-diethylamino-1-methylbutylamino)-2-methoxyacridine dihydrochloride; Atebrin dihydrochloride; Mepacrine dihydrochloride

CAS Number: 69-05-6
Empirical Formula (Hill Notation): C23H30ClN3O · 2HCl
Molecular Weight: 472.88
EC Number: 200-700-8
MDL Number: MFCD00012659
Linear Formula: C23H30ClN3O · 2HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-Q3251-25G 25 g
 $161.00
1/EA		 Add To Favorites
45-Q3251-100G 100 g
 $521.00
1/EA		 Add To Favorites

 

assay ≥90%
biological source synthetic
form powder
InChI 1S/C23H30ClN3O.2ClH/c1-5-27(6-2)13-7-8-16(3)25-23-19-11-9-17(24)14-22(19)26-21-12-10-18(28-4)15-20(21)23;;/h9-12,14-16H,5-8,13H2,1-4H3,(H,25,26);2*1H
InChI key UDKVBVICMUEIKS-UHFFFAOYSA-N
mp 257 °C
originator Bayer
Quality Level 100 
SMILES string Cl[H].Cl[H].CCN(CC)CCCC(C)Nc1c2ccc(Cl)cc2nc3ccc(OC)cc13
solubility H2O: soluble, clear to hazy
Application: Quinacrine dihydrochloride has been used:
• in its uptake and accumulation studies in mouse lung slices using fluorescence microscope
• in the staining of ATP vesicles in mesenchymal stem cells (MSCs)
• in uptake-release assay for characterization of dense granule functionality of platelets
Biochem/physiol Actions: Non-selective MAO-A/B inhibitor.
Biochem/physiol Actions: Quinacrine has anthelmintic functionality and used in the female sterilization. It is used to treat systemic lupus erythematosus and rheumatic diseases. Apart from malaria, Quinacrine is effective for treating giardia and tapeworm infections. It inhibits nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity in addition to monoamine oxidase inhibition.
Features and Benefits: This compound was developed by Bayer . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
General description: Quinacrine is an acridine derivative and a potent antimalarial agent.
Other Notes: This product is not assigned an expiration date or recommended retest date.
Preparation Note: Stock solutions are stable for up to 60 h at 20°C.
Purity ≥90%
mp 257 °C
UNSPSC 12352101

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