Quetiapine hemifumarate salt
SIGMA/Q3638 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 111974-72-2
Empirical Formula (Hill Notation): C21H25N3O2S · 0.5C4H4O4
Molecular Weight: 441.54
MDL Number: MFCD03423782
Linear Formula: C21H25N3O2S · 0.5C4H4O4
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white to off-white |
| form | powder |
| InChI | 1S/2C21H25N3O2S.C4H4O4/c2 |
| InChI key | ZTHJULTYCAQOIJ-WXXKFALUSA |
| originator | AstraZeneca |
| Quality Level | 100 ![]() |
| SMILES string | OC(=O)C=CC(O)=O.OCCOCCN |
| solubility | DMSO: >10 mg/mL |
| storage condition | desiccated |
| storage temp. | 2-8°C |
| Application: | Quetiapine hemifumarate salt has been used as an antagonist for β-arrestin 2 mutant T205M recruitment. |
| Biochem/physiol Actions: | Quetiapine hemifumarate is a combined serotonin (5HT2) and dopamine (D2) receptor antagonist. |
| Biochem/physiol Actions: | Quetiapine hemifumarate is an atypical antipsychotic, a combined serotonin (5HT2) and dopamine (D2) receptor antagonist. |
| Biochem/physiol Actions: | Quetiapine promotes oligodendrogenesis in vitro. It is used in treating depressive disorders. |
| Features and Benefits: | This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: | This compound was developed by AstraZeneca . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| General description: | Quetiapine is a derivative of dibenzothiazepine compound and is also referred to as seroquel and clemastine. |
| Packaging: | 10, 50 mg in glass bottle |
| Symbol | ![]() GHS07,GHS09 |
| Signal word | Warning |
| Hazard statements | H302 - H400 |
| Precautionary statements | P273 - P301 + P312 + P330 |
| Hazard Codes | Xn,N |
| Risk Statements | 22-50/53 |
| Safety Statements | 60-61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |



