Reveromycin A

SIGMA/R0654 - solid

CAS Number: 134615-37-5
Empirical Formula (Hill Notation): C₃₆H₅₂O₁₁
Molecular Weight: 660.79
MDL Number: MFCD00912537
Linear Formula: C₃₆H₅₂O₁₁
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-R0654-100UG	100 µg	$374.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	fungi
biological source	Streptomyces sp.
color	tan
form	solid
InChI	1S/C36H52O11/c1-6-7-19-35(47-34(44)17-16-32(40)41)21-22-36(46-30(35)14-10-25(3)23-33(42)43)20-18-27(5)29(45-36)13-9-24(2)8-12-28(37)26(4)11-15-31(38)39/h8-12,14-15,23,26-30,37H,6-7,13,16-22H2,1-5H3,(H,38,39)(H,40,41)(H,42,43)/b12-8+,14-10+,15-11+,24-9+,25-23+/t26-,27-,28-,29+,30-,35+,36-/m0/s1
InChI key	ZESGNAJSBDILTB-OXVOKJAASA-N
mode of action	protein synthesis \| interferes
mol wt	660.79 g/mol
packaging	pkg of 100 μg
Quality Level	200
shipped in	wet ice
SMILES string	[H][C@]1(CC=C(C)C=C[C@H](O)[C@@H](C)C=CC(O)=O)O[C@]2(CC[C@@H]1C)CC[C@@](CCCC)(OC(=O)CCC(O)=O)[C@@]([H])(O2)C=CC(C)=CC(O)=O
solubility	DMF: soluble
	DMSO: soluble
	ethanol: soluble
	ethyl acetate: soluble
	methanol: soluble
	soluble
storage temp.	−20°C

Analysis Note:	Avoid acidic conditions.
Biochem/physiol Actions:	It is an epidermal growth factor (EGF) and eukaryotic cell growth inhibitor.
Biochem/physiol Actions:	Reveromycin A is a polyketide antibiotic from Streptomyces sp. Epidermal growth factor (EGF) inhibitor; apoptosis inducer; G₁ phase cell cycle inhibitor having antiproliferative behavior against human cell lines KB and K562 as well as antifungal activity.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	−20°C
UNSPSC	12352207

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