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Reserpine

SIGMA/R0875

Synonym: (3β, 16β, 17α, 18β, 20α)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester

CAS Number: 50-55-5
Empirical Formula (Hill Notation): C33H40N2O9
Molecular Weight: 608.68
EC Number: 200-047-9
MDL Number: MFCD00005091
Linear Formula: C33H40N2O9
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-R0875-1G 1 g
$195.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: R0875-1G.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: R0875-1G

 

InChI 1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1
InChI key QEVHRUUCFGRFIF-MDEJGZGSSA-N
mp ~265 °C (dec.)
Quality Level 200 
SMILES string CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c6cc(OC)c(OC)c(OC)c6
Application: Reserpine has been used:
• to study its effect on minimal inhibitory concentration of trovafloxacin and ciprofloxacin
• inject rats, to study its effect on behavioural parameters such as locomotion and fear/anxiety
• as a lock spray reference compound in lipid profiling

Biochem/physiol Actions: Inhibits vesicular uptake of catecholamines and serotonin.
Biochem/physiol Actions: Reserpine is an alkaloid present in Rauwolfia species. It is useful in treating systemic hypertension, schizophrenia, psychiatric disorders and Raynaud′s syndrome. Reserpine is known to inhibit adrenaline induced-cutaneous blood vessel constriction. It diminishes the effect of hyperthyroidism on cardiovascular and nervous system.
Features and Benefits: This compound is a featured product for ADME Tox research. Click here  to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound is featured on the Biogenic Amine Transporters  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 1 g in glass bottle
mp ~265 °C (dec.)
UNSPSC 12352200

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