Reserpine
SIGMA/R0875
Synonym: (3β, 16β, 17α, 18β, 20α)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester
CAS Number: 50-55-5
Empirical Formula (Hill Notation): C33H40N2O9
Molecular Weight: 608.68
EC Number: 200-047-9
MDL Number: MFCD00005091
Linear Formula: C33H40N2O9
Product Type: Chemical
| InChI | 1S/C33H40N2O9/c1-38-19-7- |
| InChI key | QEVHRUUCFGRFIF-MDEJGZGSSA |
| mp | ~265 °C (dec.) |
| Quality Level | 200 ![]() |
| SMILES string | CO[C@H]1[C@@H](C[C@@H]2CN |
| Application: | Reserpine has been used: • to study its effect on minimal inhibitory concentration of trovafloxacin and ciprofloxacin • inject rats, to study its effect on behavioural parameters such as locomotion and fear/anxiety • as a lock spray reference compound in lipid profiling |
| Biochem/physiol Actions: | Inhibits vesicular uptake of catecholamines and serotonin. |
| Biochem/physiol Actions: | Reserpine is an alkaloid present in Rauwolfia species. It is useful in treating systemic hypertension, schizophrenia, psychiatric disorders and Raynaud′s syndrome. Reserpine is known to inhibit adrenaline induced-cutaneous blood vessel constriction. It diminishes the effect of hyperthyroidism on cardiovascular and nervous system. |
| Features and Benefits: | This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| Features and Benefits: | This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Packaging: | 1 g in glass bottle |
| Symbol | ![]() GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H302 - H336 - H351 - H360D |
| Precautionary statements | P201 - P301 + P312 + P330 - P308 + P313 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 22-36/37/39 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | ~265 °C (dec.) |
| UNSPSC | 12352200 |



