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S(−)-Raclopride (+)-tartrate salt

SIGMA/R121 - >97%, solid

Synonym: 3,5-Dichloro-N-(1-ethylpyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxybenzamide (+)-tartrate salt

CAS Number: 98185-20-7
Empirical Formula (Hill Notation): C15H20Cl2N2O3 · C4H6O6
Molecular Weight: 497.32
MDL Number: MFCD00274072
Linear Formula: C15H20Cl2N2O3 · C4H6O6
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-R121-25MG 25 mg
 $224.00
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45-R121-100MG 100 mg
 $638.00
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assay >97%
color white
form solid
InChI 1S/C15H20Cl2N2O3.C4H6O6/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2;5-1(3(7)8)2(6)4(9)10/h7,9,20H,3-6,8H2,1-2H3,(H,18,21);1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1
InChI key QULBVRZTKPQGCR-NDAAPVSOSA-N
Quality Level 100 
SMILES string O[C@H]([C@@H](O)C(O)=O)C(O)=O.CCN1CCC[C@H]1CNC(=O)c2c(O)c(Cl)cc(Cl)c2OC
solubility H2O: 89 mg/mL
Application: S(−)-Raclopride (+)-tartrate salt has been used as a D2 receptor antagonist:
• to study the role of the D2 receptor in mediating ventrolateral PAG (vlPAG)/dorsal raphe dopaminergic antinociceptive effect in animals
• in pharmacological and behavioral studies performed with Thap1 null mice
• to determine the relationship between Ca2+ transients and dopamine neuron activity in rats
Biochem/physiol Actions: Raclopride is a benzamide derivative and a selective D2 dopamine receptor antagonist.
Disclaimer: Photosensitive
Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity >97%
UNSPSC 12352200

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