Ral B human
SIGMA/R2027 - recombinant, expressed in E. coli, buffered aqueous glycerol solution
MDL Number: MFCD03792555
Product Type: Chemical
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| form | buffered aqueous glycerol solution |
| Quality Level | 200  |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| storage temp. | −20°C |
| UniProt accession no. | P11234  |
| Application: | Can be used as a control in immunoblotting and in protein binding assays. |
| Biochem/physiol Actions: | Ral B (21 kDa, native), a member of the Ras-like GTP binding protein family, is a crucial link in intracellular signaling cascades. |
| Biochem/physiol Actions: | Ral B has been implicated in invasion and metastasis of human cancer cells. Reports have shown that depletion of Ral B by siRNA results in significantly reduced migration rates of tumor cells, while constitutively active Ral B promoted migration. |
| Other Notes: | GST-tagged Ras-like fusion protein |
| Physical form: | Supplied as a solution in 50 mM Tris, pH 7.5, containing 150 mM sodium chloride, 10 mM magnesium chloride, 1 mM DTT, and 10% glycerol. |
| Safety Statements | 23-24/25 |
| WGK Germany | 1 |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |