RK-682
SIGMA/R2033 - ≥98% (HPLC)
Synonym: (R)
CAS Number: 150627-37-5
Empirical Formula (Hill Notation): C21H36O5
Molecular Weight: 368.51
MDL Number: MFCD20488046
Linear Formula: C21H36O5
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white to tan |
| form | powder |
| InChI | 1S/C21H36O5/c1-2-3-4-5-6- |
| InChI key | KZTSLHQKWLYYAC-GOSISDBHSA |
| Quality Level | 100  |
| SMILES string | CCCCCCCCCCCCCCCC(=O)C1=C( |
| solubility | DMSO, heptane and xylene: ≥8 mg/mL |
| storage temp. | −20°C |
| Application: | RK-682 has been used: • as a positive control in high-performance liquid chromatography (HPLC) • as a reference compound in high-performance liqiud chromatography (HPLC) • as a pan-protein tyrosine phosphatase non-receptor type (PTPN) inhibitor to study its effects on the activated lymphocytes |
| Biochem/physiol Actions: | RK-682 is a specific and noncompetitive inhibitor of protein tyrosine phosphatase; It inhibited dephosphorylation activity of CD45 and VHR with IC50 54 and 2.0 microM and 4.5 microM against PTP1B. |
| Biochem/physiol Actions: | Specific and noncompetitive inhibitor of protein tyrosine phosphatase. |
| Features and Benefits: | This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Packaging: | 1 mg in glass bottle |
| Packaging: | 200 μg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |