all trans-Retinal
SIGMA/R2500 - powder, ≥98%
Synonym: Vitamin A aldehyde
CAS Number: 116-31-4
Empirical Formula (Hill Notation): C20H28O
Molecular Weight: 284.44
MDL Number: MFCD00001550
Linear Formula: C20H28O
Product Type: Chemical
Representative of vacuum-sealed clear ampule packaging. Non-uniform tips are an inherent feature in this sealing process.
| assay | ≥98% |
| biological source | synthetic (organic) |
| color | yellow |
| form | powder |
| InChI | 1S/C20H28O/c1-16(8-6-9-17 |
| InChI key | NCYCYZXNIZJOKI-OVSJKPMPSA |
| mp | 62-64 °C |
| Quality Level | 200  |
| shipped in | dry ice |
| SMILES string | [H]C(=O)C=C(C)C=CC=C(C |
| storage temp. | −20°C |
| technique(s) | HPLC: suitable |
| Application: | All trans-Retinal has been used: • in optogenetic experiments • in electrophysiological experiment • to study the effect of AKR1B10 (aldo-keto reductase (AKR) superfamily member) on the conversion of retinal to retinol in the airway epithelium • in decidual transformation of human endometrial stromal cells |
| Biochem/physiol Actions: | All-trans retinal is converted to retinoic acid in vivo by the action of retinal dehydrogenase. Retinoic acid is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR) that act as transcription factors to regulate the growth and differentiation of normal and malignant cells. Retinal isomers are also chromophores that bind to opsins, a family of G-protein-linked transmembrane proteins, to form photosensitive receptors in visual and nonvisual systems. All-trans retinal is a potent photosensitizer. |
| General description: | All trans-Retinal is one of the major derivatives of vitamin A group. A variety of food serves as a source of vitamin A. It is predominant in liver and among the brightly colored vegetables. |
| Packaging: | 1 g in ampule |
| Packaging: | 25, 100, 500 mg in ampule |
| Packaging: | Sealed ampule. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% |
| mp | 62-64 °C |
| Storage Temp. | −20°C |
| UNSPSC | 12352205 |