Ropinirole hydrochloride
SIGMA/R2530 - powder, ≥98% (HPLC)
Synonym: 4-
CAS Number: 91374-20-8
Empirical Formula (Hill Notation): C16H24N2O · HCl
Molecular Weight: 296.84
MDL Number: MFCD01754173
Linear Formula: C16H24N2O · HCl
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | light yellow |
| form | powder |
| InChI | 1S/C16H24N2O.ClH/c1-3-9-1 |
| InChI key | XDXHAEQXIBQUEZ-UHFFFAOYSA |
| originator | GlaxoSmithKline |
| Quality Level | 100  |
| SMILES string | Cl.CCCN(CCC)CCc1cccc2NC(= |
| solubility | H2O: >10 mg/mL |
| storage condition | desiccated |
| Biochem/physiol Actions: | An agonist at the D2 and D3 dopamine receptor subtypes, binding with higher affinity to D3 than to D2 or D4. It has negligible effect on D1-receptors. It has medium in vitro affinity to opioid receptors. Ropinirole is said to have virtually no affinity to 5-HT1, 5-HT2, benzodiazepine, GABA, muscarinic, α1-, α2-, and β-adrenoreceptors. Used as antiparkinsonian drug. |
| Biochem/physiol Actions: | Ropinirole hydrochloride is effectively used to treat early and late Parkinson′s disease. |
| Biochem/physiol Actions: | Selective D2 dopamine receptor agonist, antiparkinsonian |
| Features and Benefits: | This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: | This compound was developed by GlaxoSmithKline . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Packaging: | 25, 100 mg in glass bottle |
| Symbol |   GHS07,GHS09 |
| Signal word | Warning |
| Hazard statements | H302 - H400 |
| Precautionary statements | P273 - P301 + P312 + P330 |
| Hazard Codes | Xn,N |
| Risk Statements | 22-50/53 |
| Safety Statements | 36-60-61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| UNSPSC | 12352200 |