Monoclonal Anti-Rhodopsin Kinase 1A antibody produced in mouse
SIGMA/R3151 - clone G8, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-GRK1a
MDL Number: MFCD03457575
Product Type: Chemical
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | G8, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 200  |
| shipped in | wet ice |
| species reactivity | rat, bovine, chicken, human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoprecipitation (IP): suitable |
| indirect immunofluorescence: suitable | |
| western blot: suitable | |
| UniProt accession no. | Q15835  |
| Application: | Monoclonal anti-rhodopsin kinase 1a antibody can be used in indirect immunofluorescence and western blotting. |
| General description: | GRK1 (rhodopsin kinase) is an enzyme that belongs to serine/threonine protein kinase family and expresses mainly in rod and cone photoreceptors. It has a crucial role in phosphorylation of photoactivated rhodopsin and hence starting steps in its deactivation. Monoclonal anti-rhodopsin kinase 1a antibody can be used in immunoprecipitation. Mouse anti-rhodopsin kinase 1a antibody reacts specifically with an epitope present in the C-terminal region of mouse, bovine, rat, chicken and human GRK1a. The product has shown no cross-reactivity with other G protein coupled kinases together with GRK1b. |
| General description: | Rhodopsin Kinase 1A encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. |
| Immunogen: | derived from human GRK1 |
| Physical form: | Supplied in phosphate buffered saline containing 0.05% sodium azide. |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |