Rifabutin

SIGMA/R3530 - >98% (HPLC), powder

Synonym: Ansamycin; Ansatipine (Farmitalia); LM-427; Mycobutin (Farmitalia)

CAS Number: 72559-06-9
Empirical Formula (Hill Notation): C₄₆H₆₂N₄O₁₁
Molecular Weight: 847.00
Linear Formula: C₄₆H₆₂N₄O₁₁
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-R3530-5MG	5 mg	$124.00 1/EA	Add To Favorites
45-R3530-25MG	25 mg	$492.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	neoplastics
assay	>98% (HPLC)
form	powder
InChI	1S/C46H62N4O11/c1-22(2)21-50-18-16-46(17-19-50)48-34-31-32-39(54)28(8)42-33(31)43(56)45(10,61-42)59-20-15-30(58-11)25(5)41(60-29(9)51)27(7)38(53)26(6)37(52)23(3)13-12-14-24(4)44(57)47-36(40(32)55)35(34)49-46/h12-15,20,22-23,25-27,30,37-38,41,49,52-54H,16-19,21H2,1-11H3,(H,47,57)/b13-12+,20-15+,24-14-/t23-,25+,26+,27+,30-,37-,38+,41+,45-/m0/s1
InChI key	ATEBXHFBFRCZMA-VXTBVIBXSA-N
mode of action	enzyme \| inhibits
originator	Johnson & Johnson
Quality Level	100
shipped in	wet ice
SMILES string	[N+H]1(CCC2(NC3=C4NC(=O)C(=C/C=C/[C@@H]([C@@H]([C@H]([C@H]([C@H]([C@@H]([C@@H]([C@H](C=CO[C@]5(Oc6c(c(c(c(c6C)[O-])C4=O)C3=N2)C5=O)C)OC)C)OC(=O)C)C)O)C)O)C)C)CC1)CC(C)C
solubility	DMSO: >5 mg/mL
storage condition	protect from light
storage temp.	−20°C

Biochem/physiol Actions:	Rifabutin is an antibiotic; antitumor.
Biochem/physiol Actions:	Rifabutin is an antibiotic; antitumor. Rifabutin interferes with HSP-90 molecular chaperone, enhances ubiquitination and protein degradation, and inactivates bacterial RNA polymerase.
Features and Benefits:	This compound was developed by Johnson & Johnson . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	>98% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

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