Rubitecan
SIGMA/R3655
Synonym: 9-nitrocamptothecin
CAS Number: 91421-42-0
Empirical Formula (Hill Notation): C20H15N3O6
Molecular Weight: 393.35
MDL Number: MFCD06656294
Linear Formula: C20H15N3O6
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: R3655-10MG.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: R3655-50MG
| assay | ≥98% (HPLC) |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C20H15N3O6/c1-2-20(26) |
| InChI key | VHXNKPBCCMUMSW-FQEVSTJZSA |
| mp | 182-186 °C |
| Quality Level | 100  |
| SMILES string | CC[C@@]1(O)C(=O)OCC2=C1C= |
| solubility | DMSO: 1 mg/mL |
| storage temp. | room temp |
| Biochem/physiol Actions: | Topoisomerase I inhibitor. Rubitecan induces protein- linked DNA single strand breaks, blocking DNA and RNA synthesis in dividing cells. This mode of action makes rubitecan a potential chemotherapeutic agent, and it has been used with some success against refractory pancreatic cancer. |
| Packaging: | 10 mg in glass insert |
| Packaging: | 50 mg in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| mp | 182-186 °C |
| Storage Temp. | room temp |
| UNSPSC | 12352204 |