Retinyl acetate
SIGMA/R4632 - synthetic, crystalline solid or supercooled liquid
Synonym: Retinol acetate; Vitamin A acetate
CAS Number: 127-47-9
Empirical Formula (Hill Notation): C22H32O2
Molecular Weight: 328.49
EC Number: 204-844-2
MDL Number: MFCD00019413
Linear Formula: C22H32O2
Product Type: Chemical
| assay | ≥90% (HPLC) |
| biological source | synthetic |
| color | light yellow to dark yellow |
| form | crystalline solid or supercooled liquid |
| InChI | 1S/C22H32O2/c1-17(9-7-10- |
| InChI key | QGNJRVVDBSJHIZ-QHLGVNSISA |
| mp | 57-58 °C |
| ~58 °C (lit.) | |
| potency | 2,600,000-2,940,000 I.U. per g |
| Quality Level | 300 ![]() |
| SMILES string | CC1=C(/C=C/C(C)=C/C=C/C(C |
| storage temp. | −20°C |
| Analysis Note: | Activity based on HPLC comparison to USP standard. |
| Application: | Retinyl acetate has been used: • to study its effects on cochlear development in mice • as a component of an internal standard to quantify antioxidants in yolk • as an internal standard to determine serum retinol concentration |
| Biochem/physiol Actions: | Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate. Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as needed. Retinyl acetate is used in a wide range of biological applications. |
| General description: | Vitamin A usually occurs in food as retinyl esters, which are the pre-formed sources of vitamin A. Retinyl acetate exists as yellow crystals and is insoluble in water. It is soluble in ethanol and oils. |
| Packaging: | 1, 5, 25, 100 g in glass bottle |
| Physical form: | Packaged as a melt and may exist as a crystalline solid or a supercooled viscous liquid |
| Symbol | GHS08 |
| Signal word | Danger |
| Hazard statements | H360D - H413 |
| Precautionary statements | P202 - P273 - P280 - P308 + P313 - P405 - P501 |
| Hazard Codes | T |
| Risk Statements | 61-38-53 |
| Safety Statements | 53-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥90% (HPLC) |
| mp | 57-58 °C; ~58 °C (lit.) |
| Storage Temp. | −20°C |
| UNSPSC | 12352205 |


