Resveratrol
SIGMA/R5010 - ≥99% (HPLC)
Synonym: 3,4′,5-Trihydroxy-trans-stilbene; 5-[(1E)
CAS Number: 501-36-0
Empirical Formula (Hill Notation): C14H12O3
Molecular Weight: 228.24
MDL Number: MFCD00133799
Linear Formula: C14H12O3
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: R5010-100MG
This image depicts SKU: R5010-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: R5010-500MG
This image depicts SKU: R5010-500MG
| application(s) | metabolomics vitamins, nutraceuticals, and natural products |
| assay | ≥99% (HPLC) |
| biological source | plant root (bushy knotweed) |
| form | powder |
| InChI | 1S/C14H12O3/c15-12-5-3-10 |
| InChI key | LUKBXSAWLPMMSZ-OWOJBTEDSA |
| Quality Level | 200  |
| SMILES string | Oc1ccc(cc1)C=Cc2cc(O)cc |
| solubility | acetone: 50 mg/mL, clear, faintly yellow |
| storage temp. | −20°C |
| Application: | Resveratrol has been used: • in entrapment experiment • to study its neuroprotective effect on retinal neuronal cell death mediated by diabetes-induced activation of Ca2+/calmodulin-dependent protein kinase II • as a standard in the assessment of stilbene content in grapevine leaf by in vivo fluorometry |
| Application: | Selective inhibitor of COX−1. |
| Biochem/physiol Actions: | Resveratrol is a phenolic phytoalexin found in grape skin and other plants. It has intracellular antioxidant activity and activates sirtuin 1 (SIRT1), a nicotinamide adenine dinucleotide (NAD+)-dependent histone deacetylase involved in mitochondrial biogenesis and the enhancement of peroxisome proliferator-g-activated receptor coactivator-1a (PGC-1a) and FOXO (forkhead box) activity. The anti-diabetic, neuroprotective and anti-adipogenic actions of resveratrol may be mediated via SIRT1 activation. Resveratrol has antiviral action against Herpes simplex virus-1 (HSV1) and HSV2. It also exhibits antitumor and phytoestrogenic biological activities. Resveratrol is known to prolong life in many species by mediating several physiological events. |
| Packaging: | 100, 500 mg in poly bottle |
| Preparation Note: | Soluble in ethanol, DMSO, and acetone. Only very slightly soluble in water (3 mg/100 mL). |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P264 - P280 - P305 + P351 + P338 - P337 + P313 |
| Hazard Codes | Xi |
| Risk Statements | 36 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | > 392.0 °F - closed cup - ( |
| Flash Point(C) | > 200.0 °C - closed cup - ( |
| Purity | ≥99% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352205 |