Anti-Rat IgG (whole molecule) antibody produced in rabbit
SIGMA/R5381 - whole antiserum
MDL Number: MFCD00162808
Product Type: Chemical
ELISA Anti-Rat IgG (whole molecule) antibody produced in Rabbit (Cat. No. R5381), followed by 1:5,000 Goat Anti-Rabbit IgG-Peroxidase (Cat. No. A0545), was serially diluted to detect Rat IgG by indirect ELISA.
| antibody form | whole antiserum |
| antibody product type | secondary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| contains | 15 mM sodium azide |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: 1:100,000 |
| quantitative precipitin assay: 2.8 mg/mL |
| Biochem/physiol Actions: | IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections. |
| Biochem/physiol Actions: | Immunoglobulin G (IgG) is a group of antibodies that are involved in modulating various immune responses. IgG activates the complement system and regulates the antibody-dependent cell-mediated cytotoxicity (ADCC). |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Immunoglobulin G (IgG) is made up of four polypeptide chains: two heavy chains (γ chains) and two light chains (κ or λ chains) which are inter linked by disulfide bonds. The Fab (fragment antigen binding) arm of IgG is formed by the VH and CH1 domains of the heavy and the light chains. The V regions of the antibody serve as the antigen-binding region. IgG class of immunoglobulins consists of four sub-classes i.e IgG1, IgG2, IgG3, and IgG4.. T |
| Physical form: | Rabbit Anti-Rat IgG is supplied as a liquid containing 0.1% sodium azide (see MSDS) as preservative. |
| Preparation Note: | treated to remove lipoproteins |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |