Retinyl acetate
SIGMA/R7882 - solid or viscous liquid, BioReagent, synthetic, suitable for cell culture
Synonym: Retinol acetate; Vitamin A acetate
CAS Number: 127-47-9
Empirical Formula (Hill Notation): C22H32O2
Molecular Weight: 328.49
EC Number: 204-844-2
MDL Number: MFCD00019413
Linear Formula: C22H32O2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: R7882-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: R7882-5G
| assay | ≥90% (HPLC) |
| biological source | synthetic |
| color | light yellow to dark yellow |
| form | solid or viscous liquid |
| InChI | 1S/C22H32O2/c1-17(9-7-10- |
| InChI key | QGNJRVVDBSJHIZ-QHLGVNSISA |
| mol wt | Mw 328.49 g/mol |
| mp | 57-58 °C |
| potency | ~2,800,000 I.U. per g |
| product line | BioReagent |
| Quality Level | 200  |
| SMILES string | CC1=C(/C=C/C(C)=C/C=C/C(C |
| solubility | absolute ethanol: 25 mg/mL (lit.) |
| storage temp. | −20°C |
| technique(s) | cell culture | mammalian: suitable |
| Application: | Retinyl acetate has been used as a standard to measure the concentration of vitamin C in high performance liquid chromatography analysis (HPLC) and as a supplement in the preparation of the complete medium. |
| Biochem/physiol Actions: | The oxidized form of retinol is retinoic acid, which has hormone-like growth factor and differentiation activity for epithelial and related cell types, especially neural cells. Retinoic acid induces embryonic stem cells to differentiate towards neural cells. Retinyl-acetate is known to be effective in treating breast cancer. |
| General description: | Retinyl-acetate is a natural and ester derivative of vitamin A. It is found in classical media formulations such as M-199; NCTC-109 and William′s Medium E. Vitamin A is a component of serum useful in most serum containing cell culture systems, which receive some level of vitamin A. |
| Other Notes: | All trans |
| Packaging: | 1, 5 g in glass bottle |
| Preparation Note: | The melting point of this material is approx. 58 °C. In order to package, it was melted and may exist as a crystalline solid or as a supercooled viscous liquid. |
| Symbol |  GHS08 |
| Signal word | Danger |
| Hazard statements | H360D - H413 |
| Precautionary statements | P202 - P273 - P280 - P308 + P313 - P405 - P501 |
| Hazard Codes | T |
| Risk Statements | 61-38-53 |
| Safety Statements | 53-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Purity | ≥90% (HPLC) |
| mp | 57-58 °C |
| Storage Temp. | −20°C |
| UNSPSC | 12352205 |