Synonym: (−)-(S)-5,6,7,8-Tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-1-naphthol hydrochloride; (−)-N 0437; N 0923; Neupro; SPM 962
CAS Number: 125572-93-2
Empirical Formula (Hill Notation): C19H25NOS·HCl
Molecular Weight: 351.93
MDL Number: MFCD00906149
Linear Formula: C19H25NOS·HCl
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white to off-white |
| form |
solid |
| InChI |
1S/C19H25NOS.ClH/c1-2-11-20(12-10-17-6-4-13-22-17)16-8-9-18-15(14-16)5-3-7-19(18)21;/h3-7,13,16,21H,2,8-12,14H2,1H3;1H/t16-;/m0./s1 |
| InChI key |
CEXBONHIOKGWNU-NTISSMGPSA-N |
| originator |
UCB Inc. |
| Quality Level |
100  |
| SMILES string |
Cl.CCCN(CCc1cccs1)[C@H]2CCc3c(O)cccc3C2 |
| solubility |
DMSO: >10 mg/mL |
| storage condition |
desiccated |
| storage temp. |
room temp |
| Biochem/physiol Actions: |
Rotigotine hydrochloride is a non-ergolinic D3/D2 and D1-dopamine agonist. It is appropriate for transdermal delivery through skin patches, that has the drug in a silicone-based adhesive matrix. |
| Biochem/physiol Actions: |
Rotigotine is a dopamine receptor agonist with preference for D3 receptors over D2 and D1. As such, it is an effective anti-Parkinsonian agent. |
| Biochem/physiol Actions: |
Rotigotine is a dopamine receptor agonist with preference for D3 receptors over D2 and D1. As such, it is an effective anti-Parkinsonian agent. Racemic rotigotine is about 50 times as potent as quinpirole, the gold standard D2 agonist. |
| Features and Benefits: |
This compound was developed by UCB Inc. . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Packaging: |
5, 25 mg in glass bottle |
| Hazard Codes |
Xn |
| Risk Statements |
22 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 2 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
room temp |
| UNSPSC |
12352200 |
