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Ribavirin

SIGMA/R9644 - antiviral

Synonym: 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide

CAS Number: 36791-04-5
Empirical Formula (Hill Notation): C8H12N4O5
Molecular Weight: 244.20
MDL Number: MFCD00058564
Linear Formula: C8H12N4O5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-R9644-10MG 10 mg
 $66.50
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45-R9644-50MG 50 mg
 $237.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: R9644-50MG

 

antibiotic activity spectrum viruses
assay ≥98% (TLC)
form powder
InChI 1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1
InChI key IWUCXVSUMQZMFG-AFCXAGJDSA-N
mode of action DNA synthesis | interferes
Quality Level 200 
SMILES string NC(=O)c1ncn(n1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O
solubility water: 19.60-20.40 mg/mL, clear, colorless to faintly yellow
storage temp. 2-8°C
Biochem/physiol Actions: Antiviral agent used against a wide variety of human viral infections, in particular, chronic hepatitis C, HIV, and adenovirus. Its metabolite, ribavirin 5′-phosphate, is an inhibitor of inosine monophosphate (IMP) dehydrogenase, but many other mechanisms of action are also supported with experimental evidence.
Biochem/physiol Actions: Antiviral agent used against a wide variety of human viral infections, in particular, chronic hepatitis C, HIV, and adenovirus. Its metabolite, ribavirin 5′-phosphate, is an inhibitor of inosine monophosphate (IMP) dehydrogenase.
Biochem/physiol Actions: Antiviral agent. Its metabolite, ribavirin 5′-phosphate, is an inhibitor of inosine monophosphate (IMP) dehydrogenase. Used to inhibit purine (GTP pools) biosynthesis at the level of inosine monophosphate (IMP) dehydrogenase and as a precursor to the di- and tri-phosphates which inhibit viral RNA-dependent RNA polymerases.
General description: Analog of the imidazole nucleotide intermediates in purine nucleotide biosynthesis.
General description: Chemical structure: nucleoside
Packaging: 10 mg in poly bottle
Packaging: 50 mg in glass bottle
Symbol GHS08  GHS08
Signal word Danger
Hazard statements H341 - H360FD
Precautionary statements P201 - P308 + P313
Hazard Codes T
Risk Statements 61
Safety Statements 53-22-45
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (TLC)
Storage Temp. 2-8°C
UNSPSC 12352202

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