Atrial Natriuretic Peptide EIA Kit

SIGMA/RAB0385 - for serum, plasma, culture supernatant and cell lysates

Synonym: Natriuretic peptides A; Prepronatriodilatin; ANP

Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-RAB0385-1KT	1 kit	$577.00 1/EA		Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay range	inter-assay cv: <15% intra-assay cv: <10% sensitivity: 1.02 pg/mL standard curve range: 0.1-1000 pg/mL
detection method	colorimetric
input	sample type serum sample type cell lysate sample type plasma sample type culture supernatant(s)
packaging	kit of 96 wells (12 strips x 8 wells)
shipped in	wet ice
species reactivity	mouse, human, rat
storage temp.	−20°C
technique(s)	ELISA: suitable
	enzyme immunoassay: suitable

Application:	Atrial Natriuretic Peptide EIA Kit has been used for the quantification of atrial natriuretic peptide (ANP) in cell culture.
Application:	For research use only. Not for use in diagnostic procedures. Atrial Natriuretic Peptide EIA Kit has been used to measure ANP levels in diabetes mellitus patients.
Biochem/physiol Actions:	Atrial natriuretic peptide (ANP) is a polypeptide hormone released in response to atrial dilation and it stimulates diuresis, natriuresis and vasorelaxation. ANP acts as an inhibitor of renin-angiotensin-aldosterone system (RAAS) pathway. It also has a major role in body fluid homeostasis and maintenance of blood pressure. Binding of ANP to receptors on target cell stimulate the production of cyclic guanosine monophosphate (GMP). Overexpression of ANP leads to congestive heart failure in the human. Experimental studies show that ANP can be used as a therapeutic for stimulating angiogenesis in ischemic tissues. N-terminal ANP prohormone functions as a biomarker for asymptomatic systolic left ventricular (LV) dysfunction, congestive heart failure and cardiovascular mortality.
General description:	The ANP Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting ANP peptide based on the principle of Competitive Enzyme Immunoassay. EIA-ANP-1 targets the common sequence of human, mouse and rat, and thus may be used to detect ANP expression in all these species with high specificity and sensitivity.
Immunogen:	Atrial Natriuretic Peptide, synthetic peptide

Symbol	GHS05
Signal word	Warning
Hazard statements	H290
RIDADR	UN 3264 8 / PGIII

Storage Temp.	−20°C
UNSPSC	41116158
Components	HRP-Streptavidin

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