Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA Kit
SIGMA/RAB0447 - for detection of phospho-stat3 (pTyr705) and pan-stat3 in human, mouse or rat cell and tissue lysates
Product Type: Chemical
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| shipped in | wet ice |
| species reactivity | human, mouse, rat |
| storage temp. | −20°C |
| technique(s) | capture ELISA: suitable |
| ELISA: suitable |
| Application: | Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA Kit has been used in enzyme-linked immunosorbent assay (ELISA) for quantitative measurement of phosphorylated signal transducer and activator of transcription3 (p-STAT3) in liver tissues. |
| General description: | Signal transducers and activators of transcription 3 (STAT3) is a transcription factor that belongs to the family of STAT proteins. The protein contains an Src homology 2 (SH2) domain for protein-protein interactions. STAT3 is activated by phosphorylation on tyrosine 705 by c-Jun N-terminal kinases (JNKs), cytokine receptor-associated kinases, nonreceptor tyrosine kinases, and growth factor receptor tyrosine kinases, in response to growth factors and cytokines. Phosphorylation of STAT3 is important for dimer formation and gene expression. STAT3 mediates the expression of a variety of genes that are involved in cell proliferation and differentiation. It also aids in pro-cancer immunity. The Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA (enzyme-linked immunosorbent assay) is a very rapid, convenient, and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates. |
| General description: | The Phospho-Stat3 (pTyr705) ELISA (Enzyme-Linked Immunosorbent Assay) kit is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates. |
| Immunogen: | Stat3 (pTyr705) synthetic phosphopeptide, Recombinant Human Stat3 |
| Symbol |   GHS05,GHS07 |
| Signal word | Warning |
| Hazard statements | H290 - H335 |
| Hazard Codes | Xi |
| Risk Statements | 37 |
| RIDADR | UN 3264 8 / PGIII |
| Storage Temp. | −20°C |
| UNSPSC | 41116158 |