Human PDCD1 / Programmed Cell Death Protein 1 ELISA Kit
SIGMA/RAB0721
Product Type: Chemical
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| assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 20 pg/mL standard curve range: 24.58-6000 pg/mL |
| detection method | colorimetric |
| input | sample type cell culture supernatant(s) sample type plasma sample type serum |
| packaging | kit of 96 wells (12 strips x 8 wells) |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| technique(s) | ELISA: suitable |
| Application: | For research use only. Not for use in diagnostic procedures. Please refer to the attached General ELISA KIT Procedure  (sandwich, competitive & Indirect ELISA) |
| Biochem/physiol Actions: | Programmed cell death protein 1 (PDCD1) plays an important role in the immune regulation by acting as a negative co-stimulatory factor. It suppresses the functions and multiplication of T cells, thereby reducing the release of IL-2 (interleukin-2), IL-10 and IFN-γ (interferon γ). In the presence of tumor microenvironment, PDCD1 along with its ligand modulates T effector functioning, thereby protecting cancer cells from immune-associated rejection. Mutation in this gene is associated with symptoms and progression of multiple sclerosis and susceptibility to systemic lupus erythematosus. |
| General description: | The antibody pair provided in this kit recognizes human Programmed Cell Death Protein 1. |
| Other Notes: | A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number. |
| Symbol |  GHS05 |
| Signal word | Warning |
| Hazard statements | H290 |
| RIDADR | UN 3264 8 / PGIII |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 41116158 |
| Components | ELISA Colorimetric TMB Reagent (HRP Substrate, Item H); ELISA Stop Solution (Item I); 20X Wash Buffer (Item B) |