Human SMPD1 ELISA
SIGMA/RAB1708 - for serum, plasma and cell culture supernatants
Product Type: Chemical
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| assay range | inter-assay cv: <12% intra-assay cv: <10% |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| technique(s) | ELISA: suitable |
| Application: | For research use only. Not for use in diagnostic procedures. Please refer to the attached Protocol   for details. |
| General description: | Sphingomyelin phosphodiesterase-1 (SMPD1) gene encodes for acid sphingomyelinase (aSMase), which is involved in the hydrolysis of sphingomyelin to ceramides and phosphorylcholine in the late endosomes and lysosomes. Ceramides act as proinflammatory and proapoptotic second messengers. Mutations in the SMPD1 gene are associated with a lack of aSMase, leading to Niemann-Pick disease type A and B. The SMPD1 gene is mapped to the human chromosome at 11p15.1–11p15.4. |
| Other Notes: | A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number. |
| Symbol |  GHS05 |
| Signal word | Warning |
| Hazard statements | H290 |
| RIDADR | UN 3264 8 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 41116158 |