Guanidine hydrochloride
SIGMA/RDD001 - anhydrous, free-flowing, Redi-Dri™, ≥99%
Synonym: Aminoformamidine hydrochloride; Aminomethanamidine hydrochloride; Guanidinium chloride
CAS Number: 50-01-1
Empirical Formula (Hill Notation): CH5N3 · HCl
Molecular Weight: 95.53
EC Number: 200-002-3
MDL Number: MFCD00013026
Linear Formula: NH2C(=NH)NH2 · HCl
Product Type: Chemical
| absorption | ≤0.10 at 260 nm in H2O at 6 M |
| assay | ≥99% |
| density | 1.3 g/cm3 (lit.) |
| grade | anhydrous |
| InChI | 1S/CH5N3.ClH/c2-1(3)4;/h( |
| InChI key | PJJJBBJSCAKJQF-UHFFFAOYSA |
| mp | 180-185 °C (lit.) |
| pH | (25 °C, 4.6 - 6/573 g/L) |
| product line | Redi-Dri™ |
| quality | free-flowing |
| Quality Level | 100 ![]() |
| SMILES string | Cl[H].NC(N)=N |
| solubility | H2O: 6 M |
| Application: | Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. |
| Legal Information: | Redi-Dri is a trademark of Sigma-Aldrich Co. LLC |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 500 g in poly bottle |
| Symbol | GHS07 |
| Signal word | Warning |
| Hazard statements | H302 + H332 - H315 - H319 |
| Precautionary statements | P261 - P264 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/38 |
| Safety Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% |
| mp | 180-185 °C (lit.) |
| Density | 1.3 g/cm3 (lit.) |
| UNSPSC | 12352107 |


