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MES sodium salt

SIGMA/RES0114M-A7

Synonym: 2-(N-Morpholino)ethanesulfonic acid sodium salt; 4-Morpholineethanesulfonic acid sodium salt

CAS Number: 71119-23-8
Empirical Formula (Hill Notation): C6H12NNaO4S
Molecular Weight: 217.22
EC Number: 275-203-2
MDL Number: MFCD00065473
Linear Formula: C6H12NNaO4S
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-RES0114M-A704X 10 kg
$8440.00
1/EA
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biological source synthetic
foreign activity Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
form powder
impurities Endotoxin and microbial, tested
InChI 1S/C6H13NO4S.Na/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);/q;+1/p-1
InChI key IRHWMYKYLWNHTL-UHFFFAOYSA-M
pKa  6.1
Quality Level 400 
SMILES string [Na+].[O-]S(=O)(=O)CCN1CCOCC1
suitability suitable for manufacturing use
technique(s) cell culture | mammalian: suitable
useful pH range 5.5-6.7
Application: MES Sodium is a biological buffer often referred to as a “Good’s” buffer. The pKa of MES is 5.96 which makes MES an ideal candidate for cell culture media and protein based buffer formulations to maintain a stable environment in solution. MES Sodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.

MES Sodium is used in cell culture media, biopharmaceutical buffer formulations both upstream and downstream and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.
General description: Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program 

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.
Legal Information: SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
Packaging: Product is available in the following package sizes:
RES0114M-A701X: 100g container
RES0114M-A702X 1kg container
RES0114M-A704X: 10kg container
RES0114M-A705X: 25kg container
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Flash Point(F) Not applicable
Flash Point(C) Not applicable
UNSPSC 12161700

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