PIPES, disodium salt
SIGMA/RES0704P-A7
Synonym: PIPES disodium salt; 1,4-
CAS Number: 76836-02-7
Empirical Formula (Hill Notation): C8H16N2Na2O6S2
Molecular Weight: 346.33
EC Number: 278-562-3
MDL Number: MFCD00064349
Linear Formula: C8H16N2Na2O6S2
Product Type: Chemical
| biological source | synthetic |
| foreign activity | Cytotoxicity, DNase, NICKase, RNase, and Protease; tested |
| form | powder |
| impurities | Endotoxin and microbial; tested |
| InChI | 1S/C8H18N2O6S2.2Na/c11-17 |
| InChI key | GMHSTJRPSVFLMT-UHFFFAOYSA |
| pKa (25 °C) | 6.8 |
| Quality Level | 400 ![]() |
| SMILES string | [Na+].[Na+].[O-]S(=O)(=O) |
| suitability | suitable for manufacturing use |
| technique(s) | cell culture | mammalian: suitable |
| useful pH range | 6.1-7.5 |
| Application: | PIPES Disodium is the sodium salt form of PIPES and is a biological buffer often referred to as a “Good’s” buffer. The pKa of PIPES is 6.8 which makes it ideal for biological applications at physiological conditions. PIPES Disodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity. PIPES Disodium can be used in a wide array of biological applications including as a component in media formulations. Specific applications include buffers for cell culture and diagnostic reagent production. |
| General description: | Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program. M-Clarity Program ![]() Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step. Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs. |
| Legal Information: | SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Packaging: | Product is available in the following package sizes: RES0704P-A701X: 100 gm container RES0704P-A702X: 1 kg container RES0704P-A704X: 10 kg container |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12161700 |

